Zatosetron

Zatosetron

Systematic (IUPAC) name
5-​chloro-​2,2-​dimethyl-​N-​(8-​methyl-​8-​azabicyclo​[3.2.1]oct-​3-​yl)-​2,3-​dihydro-​1-​benzofuran-​7-​carboxamide
Identifiers
CAS Number	123482-22-4 Y
ATC code	none
PubChem	CID: 60763
ChemSpider	54761 N
UNII	901MC95XSB Y
Chemical data
Formula	C19H25ClN2O2
Molecular mass	348.867 g/mol
SMILES CC1(CC2=C(O1)C(=CC(=C2)Cl)C(=O)NC3CC4CCC(C3)N4C)C
InChI InChI=1S/C19H25ClN2O2/c1-19(2)10-11-6-12(20)7-16(17(11)24-19)18(23)21-13-8-14-4-5-15(9-13)22(14)3/h6-7,13-15H,4-5,8-10H2,1-3H3,(H,21,23) N Key:SPKBYQZELVEOLL-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Zatosetron (LY-277,359) is a drug which acts as an antagonist at the 5HT₃ receptor It is orally active and has a long duration of action, producing antinauseant effects but without stimulating the rate of gastrointestinal transport. It is also an effective anxiolytic in both animal studies and human trials, although with some side effects at higher doses.

See also

• Ondansetron
• Bemesetron
• Granisetron
• Ricasetron
• Tropanserin
• Tropisetron