(R)-2-hydroxy-fatty-acid dehydrogenase
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| (R)-2-hydroxy-fatty-acid dehydrogenase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.1.1.98 | ||||||||
| CAS number | Template:CAS | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a (R)-2-hydroxy-fatty-acid dehydrogenase (EC 1.1.1.98) is an enzyme that catalyzes the chemical reaction
- (R)-2-hydroxystearate + NAD+
2-oxostearate + NADH + H+
Thus, the two substrates of this enzyme are (R)-2-hydroxystearate and NAD+, whereas its 3 products are 2-oxostearate, NADH, and H+. This reaction is important in fatty acid metabolism.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-2-hydroxystearate:NAD+ oxidoreductase. Other names in common use include D-2-hydroxy fatty acid dehydrogenase, and 2-hydroxy fatty acid oxidase.
References
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