AS-19 (drug)

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AS-19
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Systematic (IUPAC) name
(2S)-N,N-dimethyl-5-(1,3,5-trimethylpyrazol-4-yl)-1,2,3,4-tetrahydronaphthalen-2-amine
Identifiers
PubChem CID: 23642275
ChemSpider 24605931 YesY
Chemical data
Formula C18H25N3
Molecular mass 283.411 g/mol
  • CC1=C(C(=NN1C)C)C2=C3CC[C@@H](CC3=CC=C2)N(C)C
  • InChI=1S/C18H25N3/c1-12-18(13(2)21(5)19-12)17-8-6-7-14-11-15(20(3)4)9-10-16(14)17/h6-8,15H,9-11H2,1-5H3/t15-/m0/s1 YesY
  • Key:BTTOYOKCLDAHHO-HNNXBMFYSA-N YesY
  (verify)

AS-19 is a substance which acts as a potent agonist at the 5HT7 receptor, with an IC50 of 0.83nM. It reverses the amnesia induced by drugs such as scopolamine and dizocilpine and improves long term memory acquisition, but inhibits short term memory formation.[1][2]

See also

References

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