Annual pharmaceutical drug sales

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Annual Sales (USD Millions)

Medication Trade name Primary Indication Company 2008[1][2][3][4][5][6] 2007[7][8][9][10][11][12] 2006[13][14][15][16][17][18] 2005[19][20][21][22][23] 2004[24][25][26][27] 2003[28][29][30][31] 2002[32][33][34][35] 2001[36] 2000[37][38]
atorvastatin Lipitor Reduction of LDL cholesterol Pfizer $12,401 $12,675 $12,886 $12,187 $10,862 $9,231 $7,972 $6,448 $5,028
sunitinib malate Sutent Advanced and/or metastatic renal cell carcinoma (mRCC) & refractory gastrointestinal stromal tumors (GIST) Pfizer $847 $581 $219
irinotecan Camptosar Metastatic colorectal cancer Pfizer $563 $969 $903 $910 $554 $299
bimatoprost Lumigan Open-angle glaucoma or ocular hypertension Allergan $426.2 $391.7 $327.5 $267.6 $232.9 $181.3 $123 $35.4
exemestane Aromasin Breast cancer Pfizer $465 $401 $320 $247 $143 $58
epirubicin Ellence Breast cancer Pfizer $312 $367 $344 $216
trastuzumab Herceptin HER2-positive metastatic breast cancer Genentech $1,382 $1,287 $1,234 $747.2 $483.2 $424.8 $385.2 $346.7 $276
gemcitabine Gemzar Ovarian cancer, non-small cell lung cancer (NSCLC), metastatic breast cancer (MBC), and pancreatic cancer Eli Lilly & Co. $1,719.8 $1,592.4 $1,408.1 $1,334.5 $1,214.4 $1,021.7 $875 $723 $559.3
bevacizumab Avastin Metastatic colorectal cancer, non-small cell lung cancer (NSCLC), renal cell carcinoma, HER2-negative breast cancer Genentech $2,686 $2,296 $1,746 $1,132 $554.6
erlotinib Tarceva Advanced (metastatic) non-small cell lung cancer (NSCLC) Genentech $457 $417 $402 $274.9 $13.3
brimonidine Alphagan Open-angle glaucoma or ocular hypertension Allergan $286.8 $248.5 $250.9
rituximab Rituxan Non-Hodgkin's lymphoma and rheumatoid arthritis Genentech $2,587 $2,285 $2,071 $1,831.4 $1,574 $1,360.2 $1,162.9 $818.6
ranibizumab Lucentis Age-related macular degeneration (AMD) Genentech $875 $815 $380
omalizumab Xolair Asthma Genentech $517 $472 $425 $320.6 $187.6 $25.1
somatropin Nutropin Growth hormone deficiency, chronic renal insufficiency Genentech $358 $371 $378 $370.5 $348.8 $319.5
dornase alfa Pulmozyme Cystic fibrosis (CF) Genentech $257 $223 $199 $186.5 $157.1 $143.7 $138.1 $123
efalizumab Raptiva Plaque psoriasis Genentech $108 $107 $90 $79.2 $52.4 $1.4
montelukast Singulair Asthma Merck $4,336.9 $4,266.3 $3,579 $2,975.6 $2,622
alendronate sodium Fosamax Postmenopausal osteoporosis Merck $1,552.7 $3,049 $3,134.4 $3,191.2 $3,159.7
sitagliptin Januvia Type 2 diabetes Merck $1,397.1 $667.5 $42.9
simvastatin Zocor Reduction of LDL cholesterol Merck $660.1 $876.5 $2,802.7 $4,381.7 $5,196.5
rizatriptan benzoate Maxalt Migraine pain Merck $529.2 $467.3 $406.4 $348.4 $309.9
finasteride Propecia Hair loss Merck $429.1 $405.4 $351.8 $291.9 $270.2
etoricoxib Arcoxia Osteoarthritis and rheumatoid arthritis Merck $377.3 $329.1 $265.4 $218.2
sitagliptin/metformin HCl Janumet Type 2 diabetes Merck $351.1 $86.4
finasteride Proscar Benign prostatic hyperplasia (enlarged prostate) Merck $323.5 $411 $618.5 $741.4 $733.1
aprepitant Emend Nausea and vomiting prevention caused by chemotherapy Merck $263.8 $204.2 $130.8 $87
olanzapine Zyprexa Schizophrenia Eli Lilly & Co. $4,696.1 $4,761 $4,363.6 $4,202.3 $4,419.8 $4,276.9 $3,689 $3,087 $2,349.5
duloxetine HCl Cymbalta Depression and generalized anxiety disorder Eli Lilly & Co. $2,697.1 $2,102.9 $1,316.4 $679.7 $93.9
insulin lispro Humalog Type 1 diabetes in adults Eli Lilly & Co. $1,735.8 $1,474.6 $1,299.5 $1,197.7 $1,101.6 $1,021.3 $834 $628 $350.2
pemetrexed Alimta Locally advanced or metastatic nonsquamous non-small cell lung cancer (NSCLC) Eli Lilly & Co. $1,154.7 $854 $611.8 $463.2 $142.6
raloxifene HCl Evista Osteoporosis Eli Lilly & Co. $1,075.6 $1,090.7 $1,045.3 $1,036.1 $1,012.7 $922.1 $822 $665 $521.5
insulin isophane Humulin Diabetes Eli Lilly & Co. $1,063.2 $985.2 $925.3 $1,004.7 $997.7 $1,060.4 $1,004 $1,061 $1,114.5
teriparatide Forteo Osteoporosis Eli Lilly & Co. $778.7 $709.3 $594.3 $389.3 $238.6 $65.3
atomoxetine HCl Strattera Attention-deficit/hyperactivity disorder (ADHD) Eli Lilly & Co. $579.5 $569.4 $579 $552.1 $666.7 $370.3
timolol Istalol Open-angle glaucoma Ista Pharmaceuticals $14.6 $11.3 $8.3 $2.6
bromfenac Xibrom Ocular inflammation Ista Pharmaceuticals $63 $42.1 $20.2 $5.3
hyaluronidase Vitrase Spreading agent Ista Pharmaceuticals $5.2 $5.2 $4.2 $2.5

Notes

  1. ↑ [1], Genentech 2008 10-K.
  2. ↑ [2], Pfizer 2008 10-K.
  3. ↑ [3], Eli Lilly & Co. 2008 10-K.
  4. ↑ [4], Allergan 2008 10-K.
  5. ↑ [5], Merck 2008 10-K.
  6. ↑ [6], Ista Pharmaceuticals 2008 10-K.
  7. ↑ [7], Genentech 2007 10-K.
  8. ↑ [8], Pfizer 2007 10-K.
  9. ↑ [9], Eli Lilly & Co. 2007 10-K.
  10. ↑ [10], Allergan 2007 10-K.
  11. ↑ [11], Merck 2007 10-K.
  12. ↑ [12], Ista Pharmaceuticals 2007 10-K.
  13. ↑ [13], Genentech 2006 10-K.
  14. ↑ [14], Pfizer 2006 10-K.
  15. ↑ [15], Eli Lilly & Co. 2006 10-K.
  16. ↑ [16], Allergan 2006 10-K.
  17. ↑ [17], Merck 2006 10-K.
  18. ↑ [18], Ista Pharmaceuticals 2006 10-K.
  19. ↑ [19], Genentech 2005 10-K.
  20. ↑ [20], Pfizer 2005 10-K.
  21. ↑ [21], Eli Lilly & Co. 2005 10-K.
  22. ↑ [22], Allergan 2005 10-K.
  23. ↑ [23], Merck 2005 10-K.
  24. ↑ [24], Genentech 2004 10-K.
  25. ↑ [25], Pfizer 2004 10-K.
  26. ↑ [26], Eli Lilly & Co. 2004 10-K.
  27. ↑ [27], Allergan 2004 10-K.
  28. ↑ [28], Genentech 2003 10-K.
  29. ↑ [29], Pfizer 2003 10-K.
  30. ↑ [30], Eli Lilly & Co. 2003 10-K.
  31. ↑ [31], Allergan 2003 10-K.
  32. ↑ [32], Genentech 2002 10-K.
  33. ↑ [33], Pfizer 2002 10-K.
  34. ↑ [34], Eli Lilly & Co. 2002 10-K.
  35. ↑ [35], Allergan 2002 10-K.
  36. ↑ [36], Pfizer 2001 10-K.
  37. ↑ [37], Genentech 2000 10-K.
  38. ↑ [38], Eli Lilly & Co. 2000 10-K.
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