Aprobarbital
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| Systematic (IUPAC) name | |
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5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
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| Clinical data | |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Identifiers | |
| CAS Number | 77-02-1  Y |
| ATC code | N05CA05 (WHO) |
| PubChem | CID: 6464 |
| DrugBank | DB01352 Y |
| ChemSpider | 6221 Y |
| UNII | Q0YKG9L6RF Y |
| KEGG | D00698 Y |
| ChEBI | CHEBI:2791 Y |
| ChEMBL | CHEMBL7863 Y |
| Synonyms | aprobarbital, Oramon, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid |
| Chemical data | |
| Formula | C10H14N2O3 |
| Molecular mass | 210.23 g/mol |
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Aprobarbital (as known in the United States, or aprobarbitone (as known elsewhere), sold as Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia.[1] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.
References
- ↑ Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.
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