BD1067
From Infogalactic: the planetary knowledge core
Systematic (IUPAC) name | |
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N-[2-(3,4-dichlorophenyl)ethyl]-N-ethyl-1-pyrrolidineethanamine
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Identifiers | |
CAS Number | 138356-12-4 |
PubChem | CID: 9796923 |
ChemSpider | 7972689 |
Chemical data | |
Formula | C16H24Cl2N2 |
Molecular mass | 315.28 g/mol |
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BD1067 or N-[2-(3,4-dichlorophenyl)ethyl]-N-ethyl-1-pyrrolidineethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 2 ± 0.5 nM for the sigma-1 receptor and greater than 19 times selectivity over the sigma-2 receptor.[1]
Like other sigma receptor antagonists, pretreating Swiss Webster mice with BD1067 significantly attenuates the behavioral toxicity of cocaine.[1]
See also
References
Categories:
- Chemical articles having calculated molecular weight overwritten
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- Sigma antagonists