CAR-301,060

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CAR-301,060
CAR-301,060 structure.png
Systematic (IUPAC) name
[(7R,8R)-7-methyl-1-azabicyclo[2.2.2]octan-8-yl]2-cyclopentyl-2-hydroxy-2-phenylacetate
Identifiers
PubChem CID: 44149220
Chemical data
Formula C21H29NO3
Molecular mass 343.459 g/mol
  • C[C@@H]1[C@@H](C2CCN1CC2)OC(=O)C(C3CCCC3)(C4=CC=CC=C4)O
  (verify)

CAR-301,060 (also known as cis-2-Methyl-3-quinuclidinylphenylcyclopentylglycolate or just by its code number 301060) is a potent and long lasting anticholinergic deliriant drug, related to the chemical warfare agent 3-Quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal during the 1960s as part of the US military chemical weapons program, during research to improve upon the properties of earlier agents such as QNB.

CAR-301,060 was found to be slightly less potent than QNB, and with around the same duration of action, but with a very high central to peripheral effects ratio.[1][2]

See also

References

  1. ↑ Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents, Volume 1 (1982). Commission on Life Sciences. The National Academies Press. pp199-200.
  2. ↑ Ketchum JS. Chemical Warfare Secrets Almost Forgotton. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War. ChemBooks Inc 2006. ISBN 978-1-4243-0080-8



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