Meclofenoxate

Meclofenoxate

Systematic (IUPAC) name
2-Dimethylaminoethyl (4-chlorophenoxy)acetate
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	51-68-3 Y
ATC code	N06BX01 (WHO)
PubChem	CID: 4039
ChemSpider	3899 N
UNII	C76QQ2I0RG Y
KEGG	D00993 Y
Chemical data
Formula	C12H16ClNO3
Molecular mass	257.713
SMILES Clc1ccc(OCC(=O)OCCN(C)C)cc1
InChI InChI=1S/C12H16ClNO3/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11/h3-6H,7-9H2,1-2H3 N Key:XZTYGFHCIAKPGJ-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Meclofenoxate (Lucidril), also known as centrophenoxine, is a cholinergic drug used to treat the symptoms of senile dementia and Alzheimer's disease. It is an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA). DMAE is a natural substance, found especially in fish. pCPA is a synthetic compound that resembles a variety of plant hormones called auxins.

In elderly patients, it has been clinically shown to improve memory, have a mentally stimulating effect, and improve general cognition. Meclofenoxate also increases cellular membrane phospholipids.

Side effects and contraindications

Meclofenoxate is generally considered safe. However possible side effects may include nausea or mild dizziness. People with severely high blood pressure or convulsive disorders such as epilepsy should avoid meclofenoxate. Large doses may cause tight jaw clenching.

See also

• Cyprodenate
• ISRIB