Chlorcyclizine

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Chlorcyclizine
Chlorcyclizine.png
Systematic (IUPAC) name
1-[(4-Chlorophenyl)(phenyl)methyl]-4-methylpiperazine
Clinical data
AHFS/Drugs.com International Drug Names
MedlinePlus a682619
Legal status
  • ℞ (Prescription only)
Routes of
administration
Oral
Identifiers
CAS Number 82-93-9 YesY
ATC code R06AE04 (WHO)
PubChem CID: 2710
ChemSpider 2609 YesY
UNII M26C4IP44P YesY
ChEMBL CHEMBL22150 YesY
Chemical data
Formula C18H21ClN2
Molecular mass 300.826 g/mol
  • Clc1ccc(cc1)C(c2ccccc2)N3CCN(CC3)C
  • InChI=1S/C18H21ClN2/c1-20-11-13-21(14-12-20)18(15-5-3-2-4-6-15)16-7-9-17(19)10-8-16/h2-10,18H,11-14H2,1H3 YesY
  • Key:WFNAKBGANONZEQ-UHFFFAOYSA-N YesY
  (verify)

Chlorcyclizine (Di-Paralene, Mantadil, Pruresidine, Trihistan) is a first-generation antihistamine of the phenylpiperazine class marketed in the United States and certain other countries.[1][2][3] It is used primarily to treat allergy symptoms such as rhinitis, urticaria, and pruritus, and may also be used as an antiemetic.[1][2][3] In addition to its antihistamine effects, chlorcyclizine also has some anticholinergic, antiserotonergic, and local anesthetic properties.[4][5] It also has been studied as a potential treatment for hepatitis C.[6][7]


See also

References

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tr:Klorsiklizin