Concentrative nucleoside transporter
From Infogalactic: the planetary knowledge core
| Nucleos_tra2_C | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Nucleos_tra2_C | ||||||||
| Pfam | PF07662 | ||||||||
| InterPro | IPR011657 | ||||||||
| TCDB | 2.A.41 | ||||||||
| OPM superfamily | 454 | ||||||||
| OPM protein | 3tij | ||||||||
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Human concentrative nucleoside transporters include SLC28A1, SLC28A2 and SLC28A3 proteins. SLC28A2 is a purine-specific Na+-nucleoside cotransporter localised to the bile canalicular membrane.[1] SLC28A1 is a Na+-dependent nucleoside transporter selective for pyrimidine nucleosides and adenosine. It also transports the anti-viral nucleoside analogues Zidovudine and Zalcitabine.[2]
References
This article incorporates text from the public domain Pfam and InterPro IPR011657
