Eticyclidine

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Eticyclidine
Eticyclidine.svg
Systematic (IUPAC) name
N-ethyl-1-phenylcyclohexylamine
Clinical data
Legal status
Identifiers
CAS Number 2201-15-2 YesY
ATC code none
PubChem CID: 16622
ChemSpider 15759 YesY
UNII O8I1LL6A89 YesY
ChEMBL CHEMBL279924 YesY
Chemical data
Formula C14H21N
Molecular mass 203.323 g/mol
  • CCNC1(CCCCC1)C2=CC=CC=C2
  • InChI=1S/C14H21N/c1-2-15-14(11-7-4-8-12-14)13-9-5-3-6-10-13/h3,5-6,9-10,15H,2,4,7-8,11-12H2,1H3 YesY
  • Key:IFYLVUHLOOCYBG-UHFFFAOYSA-N YesY
  (verify)

Eticyclidine (PCE, CI-400) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400,[1] but research into PCE was not continued after the development of ketamine, a similar drug with more favourable properties.[2] PCE is slightly more potent than PCP and has similar effects, but its unpleasant taste and tendency to cause nausea made it less accepted by users.[3] Due to its similarity in effects to PCP, PCE was placed into the Schedule 1 list of illegal drugs in the 1970s, although it was only briefly abused in the 1970s and 1980s and is now little known.

See also

References

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  2. Kalir A, Edery H, Pelah Z, Balderman D, Porath G. 1-Phenylcycloalkylamine derivatives. II. Synthesis and pharmacological activity. Journal of Medicinal Chemistry. 1969. 12(3):473-477
  3. Structure Activity of PCP analogs


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