Etofibrate

Etofibrate

Systematic (IUPAC) name
2-[(pyridin-3-yl)carbonyloxy]ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
Clinical data
AHFS/Drugs.com	International Drug Names
Pharmacokinetic data
Metabolism	Hydrolyzed to clofibric acid and niacin
Identifiers
CAS Number	31637-97-5 Y
ATC code	C10AB09 (WHO)
PubChem	CID: 65777
DrugBank	DB08983 Y
ChemSpider	59197 Y
UNII	23TF67G79M Y
KEGG	D07187 Y
ChEMBL	CHEMBL358150 Y
Chemical data
Formula	C18H18ClNO5
Molecular mass	363.792 g/mol
SMILES O=C(OCCOC(=O)C(Oc1ccc(Cl)cc1)(C)C)c2cccnc2
InChI InChI=1S/C18H18ClNO5/c1-18(2,25-15-7-5-14(19)6-8-15)17(22)24-11-10-23-16(21)13-4-3-9-20-12-13/h3-9,12H,10-11H2,1-2H3 Y Key:XXRVYAFBUDSLJX-UHFFFAOYSA-N Y
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Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.