FGIN-143

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FGIN-143
FGIN-143 structure.png
Systematic (IUPAC) name
2-[2-(4-chlorophenyl)-5-chloro-1H-indol-3-yl]-N,N-dihexylacetamide
Identifiers
CAS Number 145040-29-5
PubChem CID: 3995234
Chemical data
Formula C28H36Cl2N2O
Molecular mass 487.503 g/mol
  • c3cc(Cl)ccc3-c2nc1ccc(Cl)cc1c2CC(=O)N(CCCCCC)CCCCCC
  (verify)

FGIN-1-43 is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO. It is thought to produce anxiolytic effects by stimulating steroidogenesis of neuroactive steroids such as allopregnanolone, and is several times more potent than the related drug FGIN-127.[1][2][3][4]


References

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