File:Cryptitis high mag.jpg
Summary
High magnification <a href="https://en.wikipedia.org/wiki/micrograph" class="extiw" title="w:micrograph">micrograph</a> of <a href="https://en.wikipedia.org/wiki/cryptitis" class="extiw" title="w:cryptitis">cryptitis</a> in a case of <a href="https://en.wikipedia.org/wiki/Crohn%27s_disease" class="extiw" title="w:Crohn's disease">Crohn's disease</a>. <a href="https://en.wikipedia.org/wiki/H%26E_stain" class="extiw" title="w:H&E stain">H&E stain</a>. Colonic biopsy of the <a href="https://en.wikipedia.org/wiki/mucosa" class="extiw" title="w:mucosa">mucosa</a>.
The micrograph show numerous <a href="https://en.wikipedia.org/wiki/neutrophil" class="extiw" title="w:neutrophil">neutrophils</a> within the crypt and several eosinophils. The findings in this image (alone) are not diagnostic for Crohn's disease.
The deep aspect of the biopsy has larger hyperchromatic, i.e. darker staining, nuclei, as is typical of the crypt base. The nuclei "mature", i.e. get smaller and less hyperchromatic, toward the superficial aspect; this is a normal finding, which is often absent in dysplastic lesions (e.g. <a href="https://en.wikipedia.org/wiki/tubular_adenoma" class="extiw" title="w:tubular adenoma">tubular adenoma</a>).
Related images
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<a href="//commons.wikimedia.org/wiki/File:Cryptitis_intermed_mag.jpg" class="image"><img alt="" src="https://upload.wikimedia.org/wikipedia/commons/thumb/0/04/Cryptitis_intermed_mag.jpg/120px-Cryptitis_intermed_mag.jpg" width="120" height="80" srcset="https://upload.wikimedia.org/wikipedia/commons/thumb/0/04/Cryptitis_intermed_mag.jpg/180px-Cryptitis_intermed_mag.jpg 1.5x, https://upload.wikimedia.org/wikipedia/commons/thumb/0/04/Cryptitis_intermed_mag.jpg/240px-Cryptitis_intermed_mag.jpg 2x" data-file-width="4272" data-file-height="2848"></a>
Intermed. mag.
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<a href="//commons.wikimedia.org/wiki/File:Crypt_branching_high_mag.jpg" class="image"><img alt="" src="https://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Crypt_branching_high_mag.jpg/80px-Crypt_branching_high_mag.jpg" width="80" height="120" srcset="https://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Crypt_branching_high_mag.jpg/120px-Crypt_branching_high_mag.jpg 1.5x, https://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Crypt_branching_high_mag.jpg/160px-Crypt_branching_high_mag.jpg 2x" data-file-width="2848" data-file-height="4272"></a>
High mag. view of crypt branching (feature of chronic colitis).
Licensing
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 14:32, 9 January 2017 | | 2,848 × 4,272 (4.29 MB) | 127.0.0.1 (talk) | High magnification <a href="https://en.wikipedia.org/wiki/micrograph" class="extiw" title="w:micrograph">micrograph</a> of <b><a href="https://en.wikipedia.org/wiki/cryptitis" class="extiw" title="w:cryptitis">cryptitis</a></b> in a case of <a href="https://en.wikipedia.org/wiki/Crohn%27s_disease" class="extiw" title="w:Crohn's disease">Crohn's disease</a>. <a href="https://en.wikipedia.org/wiki/H%26E_stain" class="extiw" title="w:H&E stain">H&E stain</a>. Colonic biopsy of the <a href="https://en.wikipedia.org/wiki/mucosa" class="extiw" title="w:mucosa">mucosa</a>. <p>The micrograph show numerous <a href="https://en.wikipedia.org/wiki/neutrophil" class="extiw" title="w:neutrophil">neutrophils</a> within the crypt and several eosinophils. The findings in this image (alone) are not diagnostic for Crohn's disease. </p> <p>The deep aspect of the biopsy has larger hyperchromatic, i.e. darker staining, nuclei, as is typical of the crypt base. The nuclei "mature", i.e. get smaller and less hyperchromatic, toward the superficial aspect; this is a normal finding, which is often absent in dysplastic lesions (e.g. <a href="https://en.wikipedia.org/wiki/tubular_adenoma" class="extiw" title="w:tubular adenoma">tubular adenoma</a>). </p> <h2><span class="mw-headline" id="Related_images">Related images</span></h2> <ul class="gallery mw-gallery-traditional"> <li class="gallerybox" style="width: 155px"><div style="width: 155px"> <div class="thumb" style="width: 150px;"><div style="margin:35px auto;"><a href="//commons.wikimedia.org/wiki/File:Cryptitis_intermed_mag.jpg" class="image"><img alt="" src="https://upload.wikimedia.org/wikipedia/commons/thumb/0/04/Cryptitis_intermed_mag.jpg/120px-Cryptitis_intermed_mag.jpg" width="120" height="80" srcset="https://upload.wikimedia.org/wikipedia/commons/thumb/0/04/Cryptitis_intermed_mag.jpg/180px-Cryptitis_intermed_mag.jpg 1.5x, https://upload.wikimedia.org/wikipedia/commons/thumb/0/04/Cryptitis_intermed_mag.jpg/240px-Cryptitis_intermed_mag.jpg 2x" data-file-width="4272" data-file-height="2848"></a></div></div> <div class="gallerytext"> <p>Intermed. mag. </p> </div> </div></li> <li class="gallerybox" style="width: 155px"><div style="width: 155px"> <div class="thumb" style="width: 150px;"><div style="margin:15px auto;"><a href="//commons.wikimedia.org/wiki/File:Crypt_branching_high_mag.jpg" class="image"><img alt="" src="https://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Crypt_branching_high_mag.jpg/80px-Crypt_branching_high_mag.jpg" width="80" height="120" srcset="https://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Crypt_branching_high_mag.jpg/120px-Crypt_branching_high_mag.jpg 1.5x, https://upload.wikimedia.org/wikipedia/commons/thumb/a/a7/Crypt_branching_high_mag.jpg/160px-Crypt_branching_high_mag.jpg 2x" data-file-width="2848" data-file-height="4272"></a></div></div> <div class="gallerytext"> <p>High mag. view of crypt branching (feature of chronic colitis). </p> </div> </div></li> </ul> |
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