Fusafungine

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Fusafungine
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
CAS Number 1393-87-9 YesY
ATC code R02AB03 (WHO)
DrugBank DB08965 N
UNII 65DD690W0C YesY
KEGG D08002 N
Synonyms Fusafungin
Chemical data
Formula C29H51N2O8
Molecular mass 555.72 g/mol[1]
 NYesY (what is this?)  (verify)

Fusafungine (INN), also known as fusafungin, is an active agent used in antibiotics for treatment of nasal and throat infection. It also possesses anti-inflammatory properties. Fusafungine is a mixture of enniatin cyclohexadepsipeptides made up of alternating D-α-hydroxyvaleric acid and L-N-methylamino acid residues,[2] produced by the ascomycete Fusarium lateritium, and marketed by Servier under the trade names Locabiotal, Bioparox, and Locabiosol.

According to a pooled analysis study done in the UK for the efficacy of fusafungine in rhinopharingitis, it was found that the proportion of patients who showed an improvement in symptoms from Day 0 to Day 4 of infection was 61.5% with fusafungine vs. 46.8% when compared to a placebo.[3]

References

  1. Fusafungine at MeSH
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