GBLD-345

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GBLD-345
GBLD-345 structure.png
Systematic (IUPAC) name
2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl] imidazo[2,1-f]pyridazin-6-amine
Identifiers
PubChem CID: 4602899
ChemSpider 3794457
ChEMBL CHEMBL1339029
Chemical data
Formula C21H21N5O2
Molecular mass 375.423 g/mol
  • COC1=CC=CC(CNC(C=C2)=NN3C2=NC(C4=CC=C(N)C=C4)=C3OC)=C1
  • InChI=1S/C21H21N5O2/c1-27-17-5-3-4-14(12-17)13-23-18-10-11-19-24-20(21(28-2)26(19)25-18)15-6-8-16(22)9-7-15/h3-12H,13,22H2,1-2H3,(H,23,25)
  • Key:HQRHGSRWOHGIRI-UHFFFAOYSA-N
  (verify)

GBLD-345 is an anxiolytic drug used in scientific research, which acts as a non-selective, full-efficacy positive allosteric modulator of the GABAA receptor. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[1]

References

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