Gideon Davies

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Gideon Davies
File:Professor Gideon Davies, FRS, FMedSci.jpg
Gideon Davies in 2010
Born Gideon John Davies
(1964-07-06) 6 July 1964 (age 59)[1]
Great Sutton, Cheshire
Nationality British
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Institutions <templatestyles src="Plainlist/styles.css"/>
Alma mater University of Bristol (BSc, PhD, DSc)
Thesis Phosphoglycerate kinase from Bacillus stearothermophilus (1990)
Doctoral advisor <templatestyles src="Plainlist/styles.css"/>
  • Herman Watson
  • Len Hall[4]
Doctoral students <templatestyles src="Plainlist/styles.css"/>
Notable awards <templatestyles src="Plainlist/styles.css"/>
Spouse Valérie Marie-Andrée Ducros[1]
Children Two daughters[1]
Website
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Gideon John Davies (born 1964) FRS FRSC FMedSci is a Professor of Chemistry in the York Structural Biology Laboratory (YSBL) at the University of York, in the UK.[2][10][11][12]

Education

Davies was educated at the University of Bristol where he was awarded a Bachelor of Science degree in Biochemistry and a PhD in 1990 for research on the enzyme phosphoglycerate kinase isolated from the bacterium Bacillus stearothermophilus, and supervised by Herman Watson and Len Hall.[4][13]

Career

Following his PhD, Davies did postdoctoral research at the European Molecular Biology Laboratory (EMBL) outstation in Hamburg working with Keith S. Wilson on the use of synchrotron radiation in protein crystallography and also and the Centre national de la recherche scientifique (CNRS) in Grenoble.[14] in 1990 Davies moved to York to work with Dale Wigley and Guy Dodson on DNA gyrase. He was appointed Professor at the University of York in 2001.[14] He has collaborated with Alywn Jones, Bernard Henrissat,[15][16] Steve Withers and David Vocadlo.[3]

Research

Davies research investigates the biological chemistry of carbohydrates, from their structure[17][18] to their roles in enzymology,[19][20] glycobiology,[21][22][23] use as biofuels[24][25][26] and implications for microbiota.[27][28] His research has been funded by the Biotechnology and Biological Sciences Research Council (BBSRC),[29] European Research Council (ERC) and Alzheimer's Research UK.[14]

Awards and honours

Davies was elected a Fellow of the Royal Society (FRS) in 2010. His nomination reads: <templatestyles src="Template:Blockquote/styles.css" />

Professor Gideon Davies' research is focused on "structural enzymology". In this he addresses the enzymes, and their accessory domains, that are involved in the synthesis, modification and breakdown of carbohydrates. His chemical and structural insight into protein-carbohydrate interactions and his brilliant exploitation of advanced crystallographic methods provide the basis for understanding how the chemical and structural factors in the stereochemical pathway of the enzyme:substrate complex govern specificity and catalysis. His research is having an immense impact on carbohydrate chemistry and biology and biological catalysis generally.[8]

Davies was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2014, his nomination reads<templatestyles src="Template:Blockquote/styles.css" />

Gideon Davies, who is Professor of Biological Chemistry at University of York, has made world-leading contributions to Biochemistry. He has made fundamental additions to our understanding of enzyme mechanism and carbohydrate biochemistry. As a direct result of his work into the conformation of sugars during turnover, he described the rational design of highly potent inhibitors of O-linked glucosamine modifying enzymes. These compounds are showing potential as treatments for Alzheimer's disease. Recently he has turned to study the human microbiota, which are now recognised to be an essential component of human health, and their carbohydrate metabolism is implicated in several disease states.[30]

Davies was elected a member of the European Molecular Biology Organization (EMBO) in 2010,[14] is a Fellow of the Royal Society of Chemistry (FRSC) and was awarded a Doctor of Science (DSc) degree from the University of Bristol in 2007.[9]

Personal life

Davies married Valérie Marie-Andrée Ducros[31] in 1999 and has two daughters.[1]

References

  1. ↑ 1.0 1.1 1.2 1.3 Lua error in package.lua at line 80: module 'strict' not found. (subscription required)
  2. ↑ 2.0 2.1 Gideon Davies's publications indexed by Google Scholar, a service provided by Google
  3. ↑ 3.0 3.1 Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ 4.0 4.1 Professor Gideon Davies, FMedSci, FRS Biography, University of York
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  6. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  7. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  8. ↑ 8.0 8.1 Lua error in package.lua at line 80: module 'strict' not found.
  9. ↑ 9.0 9.1 Lua error in package.lua at line 80: module 'strict' not found.
  10. ↑ List of publications from Microsoft Academic Search
  11. ↑ Gideon Davies's publications indexed by the Scopus bibliographic database, a service provided by Elsevier.
  12. ↑ Gideon Davies on TwitterLua error in Module:WikidataCheck at line 28: attempt to index field 'wikibase' (a nil value).
  13. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  14. ↑ 14.0 14.1 14.2 14.3 Professor Gideon Davies, FMedSci, FRS, University of York
  15. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  16. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  17. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  18. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  19. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  20. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  21. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  22. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  23. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  24. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  25. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  26. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  27. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  28. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  29. ↑ UK Government research grants awarded to Gideon Davies, via Research Councils UK
  30. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  31. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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