Ifoxetine

Ifoxetine

Systematic (IUPAC) name
(3R,4S)-4-(2,3-dimethylphenoxy)piperidin-3-ol
Clinical data
Legal status	Uncontrolled
Routes of administration	Oral
Identifiers
CAS Number	66208-11-5
ATC code	none
PubChem	CID: 71971
ChemSpider	64977
UNII	LHH887104B Y
ChEMBL	CHEMBL2218865
Chemical data
Formula	C13H19NO2
Molecular mass	221.30 g/mol
SMILES O(c1cccc(c1C)C)[C@H]2CCNC[C@H]2O

Ifoxetine (CGP-15,210-G) is a selective serotonin reuptake inhibitor (SSRI) which was investigated as an antidepressant in the 1980s but was never marketed. Ifoxetine selectively blocks the reuptake of serotonin in the brain supposedly without affecting it in the periphery. Supporting this claim, ifoxetine was found to be efficacious in clinical trials and was very well tolerated, producing almost no physical side effects or other complaints of significant concern.