Lanugo

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Lanugo
Lanugo.png
Classification and external resources
Specialty Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value).
ICD-10 Q84.2
ICD-9-CM 757.4
DiseasesDB 30821
Patient UK Lanugo
[[[d:Lua error in Module:Wikidata at line 863: attempt to index field 'wikibase' (a nil value).|edit on Wikidata]]]

Lanugo (/ləˈnɡ, -ˈnj-/;[1][2] from Latin lana "wool") is very fine, soft, and usually unpigmented, downy hair as can be found on the body of a fetus or newborn baby. It is the first hair to be produced by the fetal hair follicles, and it usually appears on the fetus at about five months of gestation. It is normally shed before birth, around seven or eight months of gestation but is sometimes present at birth and disappears on its own within a few days or weeks.[3]

It is replaced by hair covering the same surfaces called vellus hair, but this hair is finer and more difficult to see. The more visible hair that continues into adulthood is called terminal hair. This forms in specific areas and is hormone dependent.[4]

Occurrence

In humans

Fetal development

During human development, the lanugo grows on fetuses as a normal part of gestation, but is usually shed and replaced by vellus hair at about 33 to 36 weeks of gestational age. As the lanugo is shed from the skin, it is normal for the developing fetus to consume the hair with the fluid, since it drinks from the amniotic fluid and urinates it back into its environment. Subsequently, the lanugo contributes to the newborn baby's meconium. Some believe the presence of lanugo in newborns is a sign of premature birth but that's not always true. It has been seen on infants born at 39 weeks gestation.

Lanugo functions as an anchor to hold the vernix caseosa on the skin. This combination with vernix caseosa protects the delicate fetal skin from damage from the amniotic fluid.[5] The vernix caseosa also helps to transition the fetus to life outside the womb. It is thought to provide lubrication for birth and it is shown to affect thermoregulation, water loss, and innate immunity. Without the lanugo to anchor the vernix caseosa these functions would be lost.[6]

Malnutrition

Lanugo can be observed in malnourished patients, including those with eating disorders. When found along with other physical symptoms, for example, lanugo can help a physician make a diagnosis of anorexia nervosa or bulimia nervosa.[7]

Teratoma

It is often found in teratomas (congenital tumours).

In animals

Lanugo is also common on other animals. For example, seals[8] and elephants[9][10][11] are often born with a covering of lanugo.

Fetal whales, like humans and all other primates, also have lanugo.

References

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  2. "lanugo". Random House Webster's Unabridged Dictionary.
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  7. "Treating Eating Disorders in Primary Care", P.M. Williams, et al, American Family Physician, Vol 77 (2): January 15, 2008
  8. Lua error in package.lua at line 80: module 'strict' not found.
  9. Ecology of the Asian Elephant in Lowland Dry Zone Habitats of the Mahaweli River Basin, Sri Lanka Natarajan Ishwaran Journal of Tropical Ecology, Vol. 9, No. 2 (May, 1993), pp. 169-182
  10. The Hair, Paul MacKenzie, Elephant Information Repository website
  11. Elephant Hair, Elephant Anatomy, Animal Corner website

External links