NS-11394

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NS-11394
NS-11394 structure.png
Systematic (IUPAC) name
2-(3-[5-(2-hydroxypropan-2-yl)benzimidazol-1-yl]phenyl)benzonitrile
Identifiers
CAS Number 951650-22-9 YesY
PubChem CID: 16747643
ChemSpider 20578861 N
Chemical data
Formula C23H19N3O
Molecular mass 353.416 g/mol
  • N#Cc2ccccc2-c(ccc3)cc3-n1cnc(c4)c1ccc4C(C)(C)O
  • InChI=1S/C23H19N3O/c1-23(2,27)18-10-11-22-21(13-18)25-15-26(22)19-8-5-7-16(12-19)20-9-4-3-6-17(20)14-24/h3-13,15,27H,1-2H3 N
  • Key:HLKYSQGBIIIQJN-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

NS-11394 is a drug which acts as a subtype-selective positive allosteric modulator at GABAA receptors, with selectivity for the α3 and α5 subtypes.[1][2] It has been researched as an analgesic for use in chronic or neuropathic pain.[3]

References

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  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.


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