OX40L
From Infogalactic: the planetary knowledge core
| tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa) | |
|---|---|
| Identifiers | |
| Symbol | TNFSF4 |
| Alt. symbols | TXGP1, OX-40L, gp34, CD252 |
| Entrez | 7292 |
| HUGO | 11934 |
| OMIM | 603594 |
| RefSeq | NM_003326 |
| UniProt | P23510 |
| Other data | |
| Locus | Chr. 1 q25 |
OX40L is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation.[1] OX40L has also been designated CD252 (cluster of differentiation 252).
Various single nucleotide polymorphisms (SNPs) of the OX40L gene have been identified. For some of them association with systemic lupus erythematosus has been reported: [2] No association with occurrence of atherosclerosis has been found. [3]
References
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External links
- OX40L Protein at the US National Library of Medicine Medical Subject Headings (MeSH)
- TNFSF4 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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