Otenabant

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Otenabant
File:Otenabant.svg
Systematic (IUPAC) name
1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)piperidine-4- carboxamide
Identifiers
CAS Number 686344-29-6 YesY
ATC code none
PubChem CID: 10052040
ChemSpider 8227602 N
UNII J8211Y53EF N
KEGG D09362 YesY
ChEMBL CHEMBL562668 N
Chemical data
Formula C25H25Cl2N7O
Molecular mass 510.4 g/mol
  • CCNC1(CCN(CC1)C2=NC=NC3=C2N=C(N3C4=CC=C(C=C4)Cl)C5=CC=CC=C5Cl)C(=O)N
  • InChI=1S/C25H25Cl2N7O/c1-2-31-25(24(28)35)11-13-33(14-12-25)22-20-23(30-15-29-22)34(17-9-7-16(26)8-10-17)21(32-20)18-5-3-4-6-19(18)27/h3-10,15,31H,2,11-14H2,1H3,(H2,28,35) N
  • Key:UNAZAADNBYXMIV-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

Otenabant (CP-945,598) is a drug which acts as a potent and highly selective CB1 antagonist.[1] It was developed by Pfizer for the treatment of obesity,[2] but development for this application has been discontinued following the problems seen during clinical use of the similar drug rimonabant.[3]

See also

References

  1. Lua error in package.lua at line 80: module 'strict' not found.
  2. Woods SC. The endocannabinoid system: novel pathway for cardiometabolic Risk-factor reduction. Journal of the American Academy of Physician Assistants. 2007 Nov;Suppl Endocannabinoid:7-10. PMID 18047036
  3. http://www.pfizer.com


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