LGALS13
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Galactoside-binding soluble lectin 13 or placental protein 13 (PP13) is a protein that in humans is encoded by the LGALS13 gene.[1][2][3]
Structure and function
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene has lysophospholipase activity. It is composed of two identical subunits which are held together by disulfide bonds. This protein has structural similarity to several members of the beta-galactoside-binding S-type lectin family.[3]
Clinical significance
PP13 levels that are low in the first trimester of pregnancy confers a higher risk for developing pre-eclampsia later in pregnancy.[4]
References
Further reading
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