PSB-SB-1202
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Systematic (IUPAC) name | |
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7-pentyl-5-methoxy-3-(2-methoxybenzyl)-2H-chromen-2-one
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Identifiers | |
CAS Number | 1399049-60-5 |
PubChem | CID: 70677953 |
Chemical data | |
Formula | C23H26O4 |
Molecular mass | 366.45 |
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PSB-SB-1202 is a coumarin derivative which is an agonist at the cannabinoid receptors CB1 and CB2, with a CB1 Ki of 32nM and a CB2 Ki of 49nM.[1] It is also a weak antagonist at the related receptor GPR55, with an IC50 of 6350nM, but has no significant affinity for GPR18.[2]
See also
References
- ↑ Rempel V, Volz N, Hinz S, Karcz T, Meliciani I, Nieger M, Wenzel W, Bräse S, Müller CE. 7-Alkyl-3-benzylcoumarins: a versatile scaffold for the development of potent and selective cannabinoid receptor agonists and antagonists. Journal of Medicinal Chemistry. 2012 Sep 27;55(18):7967-77. PMID 22916707
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
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