Pentedrone

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Pentedrone
Pentedrone.svg
Systematic (IUPAC) name
(±)-1-phenyl-2-(methylamino)pentan-1-one
Clinical data
Legal status
Identifiers
CAS Number 879722-57-3 N
ATC code none
PubChem CID: 71750191
ChemSpider 26286729 YesY
UNII 2ELU1B757Q YesY
Chemical data
Formula C12H17NO
Molecular mass 191.269 g/mol
  • O=C(C(CCC)NC)C1=CC=CC=C1
  • InChI=1S/C12H17NO/c1-3-7-11(13-2)12(14)10-8-5-4-6-9-10/h4-6,8-9,11,13H,3,7H2,1-2H3 YesY
  • Key:WLIWIUNEJRETFX-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Pentedrone (also known as α-methylamino-valerophenone) is a stimulant of the cathinone class that has been sold as a designer drug and has been found since 2010 as an ingredient in a number of "bath salt" mixes sold as legal highs.[1][2][3][4][5][6][7]

Pharmacology

Pentedrone acts as a norepinephrine-dopamine reuptake inhibitor without causing their release, the same mechanism of action as methylphenidate.[8][9]

Side effects

Pentedrone has been linked to at least one death where it was combined with α-PVP and caused heart failure.[10]

Detection

A forensic standard of Pentedrone is available, and the compound has been posted on the Forendex website of potential drugs of abuse.[11]

Legal status

On January 28, 2014, the DEA listed it, along with 9 other synthetic cathinones, on the Schedule 1 with a temporary ban, effective February 27, 2014.[12]

Pentedrone is a Anlage II controlled drug in Germany.

As of October 2015 Pentedrone is a controlled substance in China.[13]

Pentedrone is banned in the Czech Republic.[14]

See also

References

  1. EMCDDA Annual Report 2010
  2. Research on Head Shop drugs in Dublin: Part 2
  3. An overview of new psychoactive substances and the outlets supplying them
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