Propamocarb

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Propamocarb
Propamocarb.svg
Names
IUPAC name
Propyl [3-(dimethylamino)propyl]carbamate
Identifiers
24579-73-5 YesY
25606-41-1 (HCl) YesY
ChEBI CHEBI:82033
ChEMBL ChEMBL1907431
ChemSpider 30114
Jmol 3D model Interactive image
PubChem 32490
  • InChI=1S/C9H20N2O2/c1-4-8-13-9(12)10-6-5-7-11(2)3/h4-8H2,1-3H3,(H,10,12)
    Key: WZZLDXDUQPOXNW-UHFFFAOYSA-N
  • InChI=1/C9H20N2O2/c1-4-8-13-9(12)10-6-5-7-11(2)3/h4-8H2,1-3H3,(H,10,12)
    Key: WZZLDXDUQPOXNW-UHFFFAOYAA
  • O=C(OCCC)NCCCN(C)C
Properties
C9H20N2O2
Molar mass 188.27 g·mol−1
Density 0.957 g/cm3
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Propamocarb is a systemic fungicide used for control of soil, root and leaf disease caused by oomycetes. It is used by watering or spraying. Propamocarb is absorbed and distributed through the plant's tissue.

Use

Propamocarb has fungicidal activity only against oomycetes.

Safety

Propamocarb has low general toxicity, and almost no teratogenicity or neurotoxicity for mammals. It is not a carcinogen nor mutagen.[1][2] Propamocarb is not susceptible to formation of resistant diseases. It is fully metabolized by plants and aquatic bacteria in a few weeks, so it is not a major ecological threat. It carries the risk of skin sensitization. Oral LD50 is 2900 mg/kg for male rats and 2000 mg/kg for female rats.[2]

In one study conducted on tobacco, cucumber and spinach, using propamocarb synthesized out of carbon C14 radionuclide, researchers stated that propamocarb is decomposed down to carbon dioxide and then incorporated into the plant's natural compounds,[2] such as amino acids.

References