Quinpirole

Quinpirole

Names
IUPAC name (4aR,8aR)-5-propyl-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrazolo[3,4-g]quinoline
Identifiers
CAS Number	80373-22-4 Y
ChEBI	CHEBI:75401 N
ChEMBL	ChEMBL240773 N
ChemSpider	49279 N
IUPHAR/BPS	2
Jmol 3D model	Interactive image
MeSH	D019257
PubChem	54562
UNII	20OP60125T N
InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 N Key: FTSUPYGMFAPCFZ-ZWNOBZJWSA-N N InChI=1/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 Key: FTSUPYGMFAPCFZ-ZWNOBZJWBQ
SMILES CCCN1CCC[C@H]2[C@H]1CC3=C(C2)NN=C3
Properties
Chemical formula	C13H21N3
Molar mass	219.33 g/mol
Vapor pressure	{{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Quinpirole is a psychoactive drug and research chemical which acts as a selective D₂ and D₃ receptor agonist. It is used in scientific research. Quinpirole has been shown to increase locomotion and sniffing behavior in mice treated with it. At least one study has found that quinpirole induces compulsive behavior symptomatic of obsessive compulsive disorder in rats. Experiments in flies found quinpirole may have neuroprotective effects against Parkinson's disease-like pathology. Moreover, in primary neuronal cultures it also reduces the rate of firing in dopaminergic neurons.

See also

• Quinelorane