Radequinil

Radequinil

Systematic (IUPAC) name
5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin-2(1H)-one
Identifiers
CAS Number	219846-31-8
ATC code	None
PubChem	CID: 22714308
ChemSpider	11584471
Chemical data
Formula	C18H14N4O3
Molecular mass	334.329 g/mol
SMILES COc1cccc(c1)c3nccc2NC(=O)\C(=C/c23)c4nc(C)on4
InChI InChI=1S/C18H14N4O3/c1-10-20-17(22-25-10)14-9-13-15(21-18(14)23)6-7-19-16(13)11-4-3-5-12(8-11)24-2/h3-9H,1-2H3,(H,21,23) Key:JQOFKKWHXGQABB-UHFFFAOYSA-N

Radequinil (INN; AC-3933) is a cognitive enhancer which acts as a partial inverse agonist of the benzodiazepine site of the GABA_A receptor. It was under development by Dainippon Sumitomo Pharma for the treatment of Alzheimer's disease and made it to phase II clinical trials but development seems to have been halted and it was never marketed.

See also

• Terbequinil