SCH 23390

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SCH 23390
SCH 23390.svg
Names
IUPAC name
7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol
Identifiers
87075-17-0 YesY
ChEBI CHEBI:73297 N
ChEMBL ChEMBL62 N
943
Jmol 3D model Interactive image
PubChem 5018
  • CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Cl
Properties
C17H18ClNO
Molar mass 287.78 g/mol
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

SCH 23390 is a synthetic compound that acts as a D1 receptor antagonist and has either minimal or negligible effects on the D2 receptor.

In a 1990 study in rats SCH 23390 offered significant protection from death in dextroamphetamine overdosage, without providing protection from death by methamphetamine overdose. The compound provided significant protection from cocaine overdose in rats only at the lowest dose tested in the measurement series. This suggested that d-amphetamine and methamphetamine at high (lethal) doses have different mechanisms of toxicity in rats.[1]

References

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