Serinolamide A

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Serinolamide A
SerinolamideA structure.png
Systematic (IUPAC) name
(R,E)-N-(1-hydroxy-3-methoxypropan-2-yl)-N-methyloctadec-4-enamide
Identifiers
CAS Number 1342300-14-4 N
PubChem CID: 56597771
ChemSpider 27025743
Chemical data
Formula C23H45NO3
Molecular mass 383.61 g/mol
  • O=C(N(C)[C@H](CO)COC)CC/C=C/CCCCCCCCCCCCC
  • InChI=1S/C23H45NO3/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)24(2)22(20-25)21-27-3/h16-17,22,25H,4-15,18-21H2,1-3H3/b17-16+/t22-/m1/s1
  • Key:CJAVPRNATZCNLN-NBRGKURFSA-N

Serinolamide A is a naturally occurring eicosanoid derivative related to anandamide, which has been isolated from the marine cyanobacteria Lyngbya majuscula and related species in the Oscillatoria family. Testing established that serinolamide A is an active cannabinoid agonist with moderate potency, having a Ki of 1300nM at CB1 and 5x selectivity over the related CB2 receptor.[1]

See also

References

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