Tesaglitazar

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Tesaglitazar
Tesaglitazar.png
Systematic (IUPAC) name
(2S)-2-Ethoxy-3-[4-[2-(4-methylsulfonyloxyphenyl)ethoxy]phenyl]propanoic acid
Identifiers
CAS Number 251565-85-2 YesY
ATC code none
PubChem CID: 208901
ChemSpider 180999 N
UNII 6734037O3L N
KEGG D01274 YesY
ChEMBL CHEMBL521632 N
Chemical data
Formula C20H24O7S
Molecular mass 408.46 g/mol
  • CCO[C@@H](CC1=CC=C(C=C1)OCCC2=CC=C(C=C2)OS(=O)(=O)C)C(=O)O
  • InChI=1S/C20H24O7S/c1-3-25-19(20(21)22)14-16-6-8-17(9-7-16)26-13-12-15-4-10-18(11-5-15)27-28(2,23)24/h4-11,19H,3,12-14H2,1-2H3,(H,21,22)/t19-/m0/s1 N
  • Key:CXGTZJYQWSUFET-IBGZPJMESA-N N
 NYesY (what is this?)  (verify)

Tesaglitazar (also known as AZ 242) is a peroxisome proliferator-activated receptor agonist with affinity to PPARα and PPARγ, proposed for the management of type 2 diabetes.[1]

The drug had completed several phase III clinical trials,[2] however in May, 2006 AstraZeneca announced that it had discontinued further development.[3]

References

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