Triflubazam

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Triflubazam
Triflubazam.svg
Systematic (IUPAC) name
1-methyl-5-phenyl-7-(trifluoromethyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
Identifiers
CAS Number 22365-40-8 YesY
PubChem CID: 31157
ChemSpider 28907 YesY
UNII 80D8H0388T YesY
Chemical data
Formula C17H13F3N2O2
Molecular mass 334.29 g/mol
  • FC(F)(C1=CC(N(C2=CC=CC=C2)C(CC(N3C)=O)=O)=C3C=C1)F
  • InChI=1S/C17H13F3N2O2/c1-21-13-8-7-11(17(18,19)20)9-14(13)22(16(24)10-15(21)23)12-5-3-2-4-6-12/h2-9H,10H2,1H3 YesY
  • Key:DMNPCIKBNDKNTO-UHFFFAOYSA-N YesY
  (verify)

Triflubazam[1] is a drug which is a 1,5-benzodiazepine derivative, related to clobazam.[2] It has sedative and anxiolytic effects, with a long half-life and duration of action.[3][4][5]

See also

References

  1. ↑ US Patent 3660381 -5-ARYL-1H-1 5-BENZODIAZEPINE-2 4-DIONES
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Itil TM, Akpinar S, Fink M: Controlled clinical and quantitative EEG studies of triflubazam (ORF 8063) in patients with anxiety syndrome. Current Therapeutic Research 1976; 19: 307-315
  4. ↑ Csanalosi I, Pereira-Oran J, Case G, et al.: Triflubazam (ORF 8063), a new benzodiazepine in anxiety neurosis. Current Therapeutic Research 1977; 22: 166-171
  5. ↑ Nicholson AN, Stone BM, Clarke CH. Effect of the 1,5-benzodiazepines, clobazam and triflubazam, on sleep in man. British Journal of Clinical Pharmacology. 1977 Oct;4(5):567-72.

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