1880 in Wales

Centuries:	17th; 18th; 19th; 20th; 21st;
Decades:	1860s; 1870s; 1880s; 1890s; 1900s;
See also:	List of years in Wales; 1880 in The United Kingdom Ireland Scotland

This article is about the particular significance of the year 1880 to Wales and its people.

Incumbents

25 February — The Resurgam, an early mechanically-powered submarine, sinks off Rhyl.
10 March — Six miners are killed in an accident at the Bedwellty Colliery, Tredegar.
29 April — At the United Kingdom general election, Wales elects 28 Liberal MPs. David Davies, Llandinam, is returned unopposed as member for Cardigan.
17 June — Rebuilt Holyhead railway station and inner harbour officially opened.
15 July — 120 miners are killed in an accident at the Risca Colliery.
3 August — Nine miners are killed in an accident at the Bersham Colliery in Wrexham.
10 December — 101 miners are killed in an accident at the Penygraig Colliery, Rhondda.

Beriah Gwynfe Evans' Owain Glyndwr, one of the first full-length plays in the Welsh language, is first performed at Llanberis.

National Eisteddfod of Wales held at Caernarfon (first "official" National Eisteddfod)

Sir William Boyd Dawkins — Early Man in Britain and his place in the Tertiary Period
Amy Dillwyn — The Rebecca Rioter

31 January — Phil Hopkins, Wales international rugby player (died 1966)
12 February — William Joseph Rhys, writer (died 1967)
17 March — Harry Grindell Matthews, inventor (died 1941)
8 April — Thomas Thomas, boxing champion (died 1911)
19 April — Jack Jenkins, Wales international rugby player (died 1971)
30 April — George Maitland Lloyd Davies, pacifist (died 1949)
9 May — Thomas Scott-Ellis, 8th Baron Howard de Walden, patron of the arts (died 1946)
11 May — David Davies, 1st Baron Davies, politician (died 1944)
22 May
- Dr Teddy Morgan, Wales international rugby player (died 1947)
- Robert John Rowlands ('Meuryn'), journalist and poet (died 1967)
31 May — Edward Tegla Davies, author (died 1967)
22 June — Rhys Gabe, rugby player (died 1967)
2 September — Isaac Daniel Hooson, poet (died 1948)
15 September — William Charles Williams, VC recipient (died 1915)
20 September — Ernie Jenkins, Wales international rugby player (died 1958)