5-epiaristolochene synthase

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5-epiaristolochene synthase
Identifiers
EC number 4.2.3.61
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

5-epiaristolochene synthase (EC 4.2.3.61, 5-epi-aristolochene synthase, tobacco epiaristolochene synthase, farnesyl pyrophosphate cyclase, EAS, TEAS) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ((+)-5-epiaristolochene-forming).[1][2][3][4][5][6] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate \rightleftharpoons (+)-5-epiaristolochene + diphosphate

Initial cyclization gives (+)-germacrene A in an enzyme bound form.

References

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External links