ACOT8

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Acyl-coenzyme A thioesterase 8 is an enzyme that in humans is encoded by the ACOT8 gene.[1][2][3][4][5]

The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Multiple transcript variants encoding several different isoforms have been found for this gene.[5]

References

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Further reading

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External links



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