Alkylmercury lyase

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alkylmercury lyase
File:3f0p.png
Structure of the mercury-bound form of E.coli MerB. PDB 3f0p [1]
Identifiers
EC number 4.99.1.2
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an alkylmercury lyase (EC 4.99.1.2) is an enzyme that catalyzes the chemical reaction

an alkylmercury + H+ \rightleftharpoons an alkane + Hg2+

Thus, the two substrates of this enzyme are alkylmercury and H+, whereas its two products are alkane and a mercury ion.

This enzyme belongs to the family of lyases, specifically the "catch-all" class of lyases that do not fit into any other sub-class. The systematic name of this enzyme class is alkylmercury mercuric-lyase (alkane-forming). Other names in common use include organomercury lyase, organomercurial lyase, and alkylmercury mercuric-lyase.

The enzyme converts methyl mercury to the much less toxic elemental form of the metal.

References

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