Cefditoren
| 200px | |
| Systematic (IUPAC) name | |
|---|---|
|
(7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((Z)-2-(4-methylthiazol-5-yl)vinyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
|
|
| Clinical data | |
| Trade names | Spectracef |
| AHFS/Drugs.com | monograph |
| MedlinePlus | a605003 |
| Identifiers | |
| CAS Number | 104145-95-1  |
| ATC code | J01DD16 (WHO) |
| PubChem | CID: 9870843 |
| DrugBank | DB01066  |
| ChemSpider | 8046534 |
| UNII | 81QS09V3YW |
| KEGG | D07639 |
| ChEBI | CHEBI:59343 |
| ChEMBL | CHEMBL610374 |
| Chemical data | |
| Formula | C19H18N6O5S3 |
| Molecular mass | 506.58 g/mol |
|
|
|
|
| (what is this?) (verify) |
|
Cefditoren is a third-generation cephalosporin antibiotic for oral use. It is commonly marketed under the trade name Spectracef by Vansen Pharma Inc.
Cefditoren is also marketed under the name Meiact by Meiji Seika Pharma Co., Ltd.[1]
Contents
Spectrum of bacterial susceptibility
Cefditoren has a broad spectrum of activity and has been used to treat bacterial infections of the skin and respiratory tract, including bronchitis, pneumonia, and tonsillitis. The following represents MIC susceptibility data for a few medically significant microorganisms.
- Haemophilus influenzae: ≥0.063 - 0.25 μg/ml
- Staphylcoccus aureus: 0.25 - >128 μg/ml (includes MRSA)
- Streptococcus pyogenes: ≤0.004 - 2 μg/ml[2]
Cefditoren is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria, but does not have antibacterial activity against Pseudomonas aeruginosa.[3]
Clinical use
<templatestyles src="Module:Hatnote/styles.css"></templatestyles>
Indications
Cefditoren is used to treat uncomplicated skin and skin structure infections, community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, pharyngitis, and tonsillitis.
Formulations
Cefditoren is available as 200- and 400-mg tablets. It can be formulated as the prodrug cefditoren pivoxil.
References
- ↑ Meiact Full Description
- ↑ http://www.toku-e.com/Assets/MIC/Cefditoren%20sodium.pdf
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
