Cytoglobin
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Cytoglobin is the protein product of CYGB, a human and mammalian gene.[1]
Cytoglobin is a globin molecule ubiquitously expressed in all tissues and most notably utilized in marine mammals. It was discovered in 2001[2] and named cytoglobin in 2002.[3] It is thought to protect against hypoxia. The predicted function of cytoglobin is the transfer of oxygen from arterial blood to the brain.[4]
Function
Cytoglobin is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or reactive oxygen species, or serve a protective function during oxidative stress.[1][5]
Applications
CYGB expression can be used as a specific marker with which hepatic stellate cells can be distinguished from portal myofibroblasts in the damaged human liver.[6]
References
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Further reading
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External links
- cytoglobin at the US National Library of Medicine Medical Subject Headings (MeSH)
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