Hinokitiol
From Infogalactic: the planetary knowledge core
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Names | |||
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IUPAC name
2-Hydroxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one
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Other names
β-Thujaplicin; 4-Isopropyltropolone
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Identifiers | |||
499-44-5 | |||
ChEBI | CHEBI:10447 | ||
ChEMBL | ChEMBL48310 | ||
ChemSpider | 3485 | ||
Jmol 3D model | Interactive image | ||
KEGG | D04876 | ||
PubChem | 3611 | ||
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Properties | |||
C10H12O2 | |||
Molar mass | 164.20 g·mol−1 | ||
Appearance | Colorless to pale yellow crystals | ||
Melting point | 50 to 52 °C (122 to 126 °F; 323 to 325 K) | ||
Boiling point | 140 °C (284 °F; 413 K) at 10 mmHg | ||
Vapor pressure | {{{value}}} | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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verify (what is ?) | |||
Infobox references | |||
Hinokitiol (β-thujaplicin) is a natural monoterpenoid found in the wood of trees in the family Cupressaceae. It is a tropolone derivative and one of the thujaplicins.[2] Hinokitiol has inhibitory effects on Chlamydia trachomatis and may be clinically useful as a topical drug.[3][4]
The name originates from the fact it was originally isolated in Taiwanese hinoki in 1936.[5] It is actually almost absent in Japanese hinoki while it is contained in high concentration (about 0.04% of heartwood mass) in Juniperus cedrus, Hiba cedar wood (Thujopsis dolabrata) and Western red cedar (Thuja plicata). It can be readily extracted from the cedarwood with solvent and ultrasonication.[6]
References
- ↑ β-Thujaplicin at Sigma-Aldrich
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Chedgy, Russell. Secondary metabolites of Western red cedar (Thuja plicata): their biotechnological applications and role in conferring natural durability. LAP Lambert Academic Publishing, 2010, ISBN 3-8383-4661-0, ISBN 978-3-8383-4661-8
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.