KIF22
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Kinesin-like protein KIF22 is a protein that in humans is encoded by the KIF22 gene.[1][2][3]
The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests an essential role in metaphase chromosome alignment and maintenance.[3]
Interactions
KIF22 has been shown to interact with SIAH1.[4]
Clinical relevance
Mutations in this gene have been shown to cause developmental disorders such as Spondyloepimetaphyseal dysplasia with joint laxity.[5]
References
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