L-rhamnonate dehydratase

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L-rhamnonate dehydratase
Identifiers
EC number 4.2.1.90
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a L-rhamnonate dehydratase (EC 4.2.1.90) is an enzyme that catalyzes the chemical reaction

L-rhamnonate \rightleftharpoons 2-dehydro-3-deoxy-L-rhamnonate + H2O

Hence, this enzyme has one substrate, L-rhamnonate, and two products, 2-dehydro-3-deoxy-L-rhamnonate and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is L-rhamnonate hydro-lyase (2-dehydro-3-deoxy-L-rhamnonate-forming). This enzyme is also called L-rhamnonate hydro-lyase. This enzyme participates in fructose and mannose metabolism.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 2GSH, 2OZ3, 2P0I, and 2P3Z.

References

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