Long-chain-enoyl-CoA hydratase
From Infogalactic: the planetary knowledge core
| long-chain-enoyl-CoA hydratase | |||||||||
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| Identifiers | |||||||||
| EC number | 4.2.1.74 | ||||||||
| CAS number | Template:CAS | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a long-chain-enoyl-CoA hydratase (EC 4.2.1.74) is an enzyme that catalyzes the chemical reaction
- (3S)-3-hydroxyacyl-CoA
trans-2-enoyl-CoA + H2O
Hence, this enzyme has one substrate, (3S)-3-hydroxyacyl-CoA, and two products, trans-2-enoyl-CoA and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase. This enzyme is also called long-chain enoyl coenzyme A hydratase. This enzyme participates in fatty acid elongation in mitochondria and fatty acid metabolism.
References
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