RGS20

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Regulator of G-protein signaling 20 is a protein that in humans is encoded by the RGS20 gene.[1][2][3]

Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.[supplied by OMIM][3]

In melanocytic cells RGS20 gene expression may be regulated by MITF.[4]

Interactions

RGS20 has been shown to interact with GNAO1[5] and GNAZ.[1][6]

References

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Further reading

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