Ribose 1-dehydrogenase (NADP+)

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ribose 1-dehydrogenase (NADP+)
Identifiers
EC number 1.1.1.115
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a ribose 1-dehydrogenase (NADP+) (EC 1.1.1.115) is an enzyme that catalyzes the chemical reaction

D-ribose + NADP+ + H2O \rightleftharpoons D-ribonate + NADPH + H+

The three substrates of this enzyme are D-ribose, NADP+, and H2O, whereas its 3 products are D-ribonate, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-ribose:NADP+ 1-oxidoreductase. Other names in common use include D-ribose dehydrogenase (NADP+), NADP+-pentose-dehydrogenase, and ribose 1-dehydrogenase (NADP+).

References

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