S-(hydroxymethyl)glutathione synthase
| S-(hydroxymethyl)glutathione synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.4.1.22 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a S-(hydroxymethyl)glutathione synthase (EC 4.4.1.22) is an enzyme that catalyzes the chemical reaction
- S-(hydroxymethyl)glutathione
glutathione + formaldehyde
Hence, this enzyme has one substrate, S-(hydroxymethyl)glutathione, and two products, glutathione and formaldehyde.
This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming). Other names in common use include glutathione-dependent formaldehyde-activating enzyme, Gfa, and S-(hydroxymethyl)glutathione formaldehyde-lyase. This enzyme participates in methane metabolism.
References
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