Template:PBB/2539

Glucose-6-phosphate dehydrogenase
PDB rendering based on 1qki.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1QKI, 2BH9, 2BHL
Identifiers
Symbols	G6PD ; G6PD1
External IDs	OMIM: 305900 MGI: 105979 HomoloGene: 37906 ChEMBL: 5347 GeneCards: G6PD Gene
EC number	1.1.1.49
Gene ontology Molecular function • glucose-6-phosphate dehydrogenase activity • protein binding • glucose binding • identical protein binding • protein homodimerization activity • NADP binding Cellular component • nucleus • cytoplasm • centrosome • microtubule organizing center • cytosol • cytoplasmic side of plasma membrane • membrane • intracellular membrane-bounded organelle • extracellular exosome Biological process • cytokine production • carbohydrate metabolic process • glucose metabolic process • pentose-phosphate shunt • transcription initiation from RNA polymerase II promoter • lipid metabolic process • cholesterol biosynthetic process • NADP metabolic process • NADPH regeneration • glutathione metabolic process • pentose-phosphate shunt, oxidative branch • gene expression • negative regulation of protein glutathionylation • response to organic cyclic compound • pentose biosynthetic process • substantia nigra development • response to food • cellular response to oxidative stress • erythrocyte maturation • regulation of neuron apoptotic process • small molecule metabolic process • response to ethanol • ribose phosphate biosynthetic process • glucose 6-phosphate metabolic process • oxidation-reduction process Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2539	14381
Ensembl	ENSG00000160211	ENSMUSG00000031400
UniProt	P11413	Q00612
RefSeq (mRNA)	NM_000402	NM_008062
RefSeq (protein)	NP_000393	NP_032088
Location (UCSC)	Chr X: 154.53 – 154.55 Mb	Chr X: 74.41 – 74.43 Mb
PubMed search	[1]	[2]