Template:PBB/7299

Tyrosinase
Tyrosinase
Identifiers
Symbols	TYR ; ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3
External IDs	OMIM: 606933 MGI: 98880 HomoloGene: 30969 ChEMBL: 1973 GeneCards: TYR Gene
EC number	1.14.18.1
Gene ontology
Molecular function	• monooxygenase activity; • monophenol monooxygenase activity; • copper ion binding; • protein binding; • protein homodimerization activity; • protein heterodimerization activity;
Cellular component	• nucleus; • cytoplasm; • lysosome; • Golgi-associated vesicle; • cytosol; • integral component of membrane; • melanosome membrane; • melanosome; • perinuclear region of cytoplasm;
Biological process	• melanin biosynthetic process from tyrosine; • eye pigment biosynthetic process; • visual perception; • cell proliferation; • response to UV; • response to vitamin D; • cellular nitrogen compound metabolic process; • melanin biosynthetic process; • small molecule metabolic process; • thymus development; • response to cAMP; • oxidation-reduction process;
	Sources: Amigo / QuickGO
RNA expression pattern
	More reference expression data
Orthologs
Species	Human
Entrez	7299
Ensembl	ENSG00000077498
UniProt	P14679
RefSeq (mRNA)	NM_000372
RefSeq (protein)	NP_000363
Location (UCSC)	Chr 11:; 89.18 – 89.3 Mb
PubMed search	[1]
	v; t; e;

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