SERPINA9
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| Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | SERPINA9 ; GCET1; SERPINA11; SERPINA11b | ||||||||||||
| External IDs | OMIM: 615677 MGI: 1919157 HomoloGene: 23633 GeneCards: SERPINA9 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 327657 | 71907 | |||||||||||
| Ensembl | ENSG00000170054 | ENSMUSG00000058260 | |||||||||||
| UniProt | Q86WD7 | Q9D7D2 | |||||||||||
| RefSeq (mRNA) | NM_001042518 | NM_027997 | |||||||||||
| RefSeq (protein) | NP_001035983 | NP_082273 | |||||||||||
| Location (UCSC) | Chr 14: 94.46 – 94.48 Mb |
Chr 12: 103.99 – 104.01 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Serpin A9 also known as centerin or GCET1 is a protein that in humans is encoded by the SERPINA9 gene located on chromosome 14q32.1.[1] Serpin A9 is a member of the serpin family of serine protease inhibitors.
Function
The expression of SERPINA9 is restricted to germinal center B cells and lymphoid malignancies. SERPINA9 is likely to function in vivo in the germinal center as an efficient inhibitor of trypsin-like proteases.[2][3][4]
References
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External links
- The MEROPS online database for peptidases and their inhibitors: I04.082
- SERPINA9 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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