Template:PBB/554
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Arginine vasopressin receptor 2
Available structures
PDB
Ortholog search:
PDBe
,
RCSB
List of PDB id codes
4JQI
Identifiers
Symbols
AVPR2
; ADHR; DI1; DIR; DIR3; NDI; V2R
External IDs
OMIM
:
300538
MGI
:
88123
HomoloGene
:
20064
IUPHAR
:
368
ChEMBL
:
1790
GeneCards
:
AVPR2 Gene
Gene ontology
Molecular function
•
vasopressin receptor activity
•
protein binding
•
peptide binding
Cellular component
•
endosome
•
endoplasmic reticulum
•
Golgi apparatus
•
plasma membrane
•
integral component of plasma membrane
•
integral component of membrane
Biological process
•
regulation of systemic arterial blood pressure by vasopressin
•
positive regulation of systemic arterial blood pressure
•
renal water homeostasis
•
water transport
•
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
•
activation of adenylate cyclase activity
•
I-kappaB kinase/NF-kappaB signaling
•
excretion
•
hemostasis
•
positive regulation of cell proliferation
•
positive regulation of gene expression
•
telencephalon development
•
positive regulation of protein ubiquitination
•
interferon-gamma production
•
cellular response to hormone stimulus
•
response to cytokine
•
negative regulation of urine volume
•
negative regulation of renal sodium excretion
•
positive regulation of vasoconstriction
•
transmembrane transport
•
response to peptide
Sources:
Amigo
/
QuickGO
Orthologs
Species
Human
Mouse
Entrez
554
12000
Ensembl
ENSG00000126895
ENSMUSG00000031390
UniProt
P30518
O88721
RefSeq (mRNA)
NM_000054
NM_001276298
RefSeq (protein)
NP_000045
NP_001263227
Location (UCSC)
Chr X:
153.9 – 153.91 Mb
Chr X:
73.89 – 73.9 Mb
PubMed
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[2]
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