Tenatoprazole
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Tenatoprazole is a proton pump inhibitor drug candidate that was undergoing clinical testing as a potential treatment for reflux oesophagitis and peptic ulcer as far back as 2003.[1] The compound was invented by Mitsubishi Tanabe Pharma and was licensed to Negma Laboratories (part of Wockhardt as of 2007[2]).[3]:22
Mitsubishi reported that tenatoprazole was still in Phase I clinical trials in 2007[4]:27 and again in 2012.[3]:17
Tenatoprazole has an imidazopyridine ring in place of the benzimidazole moiety found in other proton pump inhibitors, and has a half-life about seven times longer than other PPIs.[5]
See also
References
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<references />, or <references group="..." />- ↑ DataMonitor. March 2003. Gastrointestinal Disease Update: Digestive Disease Week 2003
- ↑ Economic Times. 3 March, 2011. Investors unwilling to forgive Wockhardt, promoter for failings
- ↑ 3.0 3.1 Mitsubishi Tanabe Pharma State of New Product Development (as of May 8, 2012)
- ↑ Mitsubishi Tanabe Pharma FY2007 Interim Financial Results
- ↑ Li H et al. H+/K+-ATPase inhibitors: a patent review. Expert Opin Ther Pat. 2013 Jan;23(1):99-111. PMID 23205582
